Paracetamol and Autism: What Research Shows

Recent studies indicate no concrete link between paracetamol use during pregnancy and autism or ADHD in children.

A team of experts reviewed extensive research and concluded that paracetamol is generally safe when used appropriately.

Background of the Debate

In late september 2025, a global debate emerged over the use of paracetamol during pregnancy.

On september 23, 2025, US President donald trump advised pregnant women against using paracetamol, raising widespread concerns.

The drug is one of the most commonly used pain relievers, with nearly 50% of pregnant women in the US taking it.

Autism Cases and Misconceptions

Global autism rates in children have risen, prompting research into potential causes.

Earlier reports suggested a link between paracetamol use and autism, but experts now attribute the rise to improved diagnosis, not the drug itself.

Findings from Major Reviews

The british Medical Journal published the largest review, analyzing 9 systematic reviews and 40 studies on paracetamol and autism risk.

Professor shakeela Thangarathinam (University of Liverpool) stated:

“Current evidence does not confirm any link between paracetamol and autism.”

Treating high fever during pregnancy is crucial, and paracetamol remains a safe option for pain and fever.

Key Study Insights

Most reviews deny any link between paracetamol and autism.

A few studies raised potential concerns, but these were associated with genetics or maternal health factors.

A Swedish study of over 2 million children found slightly higher autism/ADHD rates with maternal paracetamol use, but experts attributed this to other factors.

Safety Considerations

Excessive or frequent use of paracetamol can be harmful.

Risks include liver failure, high blood pressure, gastrointestinal bleeding, and heart disease.

Experts advise using paracetamol only when necessary and avoiding regular use without medical guidance.

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