Telangana Hyderabad - Blood test can detect breast cancer!
Geneticists from hyderabad and trivandrum have discovered a unique strategy to use miRNA signatures for the early identification of the disease, which might lead to the development of a non-invasive, rapid, reliable, and economical blood test method for the diagnosis of breast cancer in women shortly.
The study by genetic researchers may be able to end the persistent stigma and hesitation among women to have a physical breast examination and then mammography for diagnosis. The research was recently published in Cell Communications and Signalling, a peer-reviewed science journal of UK-based Biomed Central (BMC) (February 2024).
The study by genetic researchers may be able to end the persistent stigma and hesitation among women to have a physical breast examination and then mammography for diagnosis. The research was recently published in Cell Communications and Signalling, a peer-reviewed science journal of UK-based Biomed Central (BMC) (February 2024).
In cooperation with their colleagues at the Regional cancer Centre (RCC), Medical College, trivandrum, researchers from the Hyderabad-based Centre for Cellular and Molecular Biology (CCMB) stated: "This study revealed potential biomarkers for robust classification as well as rapid, cost-effective, and early detection of IDC of breast cancer." Our research has yielded a fresher understanding of the miRNA signatures for IDC categorization and early detection.
Eighty to eighty-five percent of all cases of breast cancer are invasive ductal carcinoma (IDC), the most prevalent kind of the disease. Five years ago, the majority of cancer cases in india were caused by cervical cancer; however, as of right now, breast cancer is the leading cause of cancer in women. In india, there are 1.9–2 lakh instances of breast cancer annually, or 24–26% of all cases.
"Our results provide robust evidence that this approach can accurately differentiate IDC by type, grade, and stage," the research, which analyzed 100 breast cancer samples, stated. 34 new miRNAs that are uniquely linked to human invasive ductal carcinoma (IDC) were found using our methodology. Additionally, we looked at the precise function of these miRNAs as tumor suppressors or oncogenes.
"The first to report a set of validated novel and signature miRNAs, which could potentially serve as IDC biomarkers across specific types, grades, and various stages of cancer," according to the researchers, describes the study.